Mon. Oct 5th, 2026

This Mediterranean 45g Protein Creamy Alfredo Chicken Lasagna has a creamy and cheesy texture. We prepare this lasagna with chicken, lasagna noodles, spinach, mozzarella cheese, Parmesan cheese, Greek yogurt, cream cheese, milk, garlic, olive oil, basil, and oregano. This lasagna has approximately 590 calories and 45 g of protein. We make this Mediterranean 45g Protein Creamy Alfredo Chicken Lasagna in about 1 hour and 5 minutes. You can prepare this lasagna ahead because we refrigerate it for 4 days and freeze it for almost 3 months. You can serve this lasagna with Greek salad, cucumber tomato salad, garlic roasted broccoli, lemon herb zucchini, or tzatziki.

STATS:

  • Course: Lunch, Dinner
  • No. of Calories: 590 kcal
  • Diet: High-Protein, Mediterranean
  • Prep time: 25 minutes
  • Cuisine: Mediterranean, Italian
  • Cook time: 40 minutes
  • Portion size: 1 slice
  • Cooking mode: Oven
  • Total servings: 6
  • Difficulty level: Medium
  • Total time: 1 hour 5 minutes

TOOLS:

  • Baking dish
  • Pot
  • Skillet
  • Bowl
  • Whisk
  • Knife
  • Measuring cups and spoons
  • Aluminum foil
  • Cutting board

INGREDIENTS:

  • 12 lasagna noodles
  • 1 lb. chicken breast
  • 2 tbsp olive oil
  • 3 garlic cloves
  • 2 cups spinach
  • 1 cup Greek yogurt
  • 2 cups milk
  • 4 oz cream cheese
  • ½ cup Parmesan cheese
  • 1½ cups mozzarella cheese
  • ½ cup chicken broth
  • 1 tsp oregano
  • 1 tsp basil
  • ½ tsp Italian seasoning
  • ½ tsp black pepper
  • ¼ tsp red pepper flakes
  • 2 tbsp parsley
  • ¼ tsp lemon zest
  • ½ tsp salt

INGREDIENT NOTES AND THEIR SUBSTITUTIONS:

CHICKEN:

  • We use cooked chicken breast to provide lean protein and a tender texture. As a replacement, you can use cooked turkey or rotisserie chicken.

SPINACH:

  • We use spinach to add freshness, color, and nutrients to the lasagna. As an alternative, you can use kale or Swiss chard.

CREAM CHEESE:

  • Cream cheese provides a smooth and creamy Alfredo texture. Include Neufchâtel cheese if you are not using cream cheese.

MOZZARELLA:

  • Mozzarella provides a soft, cheesy, and melted topping. You can use low-fat mozzarella if preferred.

PARMESAN:

  • Parmesan provides a rich and salty flavor to the sauce. Pecorino Romano is a suitable replacement.

OLIVE OIL:

  • Olive oil includes healthy fats and Mediterranean taste in the recipe. Avocado oil is good to include as a substitute.

GARLIC:

  • We use fresh garlic to include a delicious savory flavor in the lasagna. You may also use 1 tsp garlic powder as an alternative.

LASAGNA NOODLES:

  • Lasagna noodles provide the classic layered structure. Whole-wheat or gluten-free noodles can be used.

OREGANO AND BASIL:

  • These herbs provide Mediterranean-inspired flavor. Fresh herbs can be used instead of dried herbs.

INSTRUCTIONS:

  1. First, cook the lasagna noodles as per package guidelines and drain them properly.
  2. Warm the oil in the skillet and cook the garlic for 30 seconds, then cook the spinach till it wilts.
  3. Include cooked chicken, oregano, basil, Italian seasoning, salt, pepper, and red pepper flakes.
  4. In the saucepan, warm the milk, cream cheese, and chicken broth to make the smooth mixture.
  5. Cool the sauce completely, then mix Greek yogurt, lemon zest, and Parmesan.
  6. Spread the Alfredo sauce in the dish, then include noodles, chicken mixture, Alfredo sauce, and mozzarella.
  7. Repeat the layers and lastly add Alfredo sauce and mozzarella then cover the dish with foil and bake for 25 minutes at 375°F.
  8. Then remove the foil and bake the lasagna for another fifteen minutes.
  9. Lastly, cool the lasagna for 15 minutes, then garnish with parsley and serve.

TIPS:

  • Strain out the spinach properly to avoid watery lasagna.
  • Avoid cooking the noodles for extra time.
  • Cool the Alfredo sauce lightly and then include the Greek yogurt.
  • We utilize freshly shredded mozzarella for perfect melting.
  • Cool the lasagna for some time and then make slices to keep the layers intact.

SERVING SUGGESTIONS:

FRESH SALADS:

  • Greek Salad
  • Cucumber Tomato Salad
  • Mediterranean Chickpea Salad
  • Lemon Herb Green Salad

ROASTED VEGETABLES:

  • Garlic Roasted Broccoli
  • Lemon Herb Zucchini
  • Roasted Bell Peppers
  • Roasted Asparagus

LIGHT SIDES:

  • Steamed Green Beans
  • Garlic Sautéed Spinach
  • Lemon Cauliflower

MEDITERRANEAN DIPS:

  • Tzatziki
  • Hummus
  • Garlic Yogurt Dip
  • Roasted Red Pepper Dip

STORAGE INFORMATION:

FRIDGE:

  • Include the cooled lasagna in a closed box then store for four days.

FREEZER:

  • Store individual portions in a closed bag for almost 3 months.

FAQs:

May we prepare this lasagna earlier?

  • Yes, you can assemble the lasagna more than twenty-four hours beforehand, chill it, and then bake.

Will we utilize rotisserie chicken?

  • Yes, you can use shredded rotisserie chicken, as it works nicely in this lasagna.

Could we increase the protein?

  • Yes, you can use additional chicken or utilize high-protein lasagna noodles.

May we prepare this lasagna gluten-free?

  • Yes, you can use non-gluten lasagna noodles and monitor every packaged element.

Will we include extra veggies?

  • Yes, you can use broccoli, mushrooms, bell peppers, or zucchini.

NUTRITIONAL INFORMATIONS:

Proteins: 45 g

Caloric Content: 590 kcal

Net carbs: 39 g

Sodium: 760 mg

Fiber: 4 g

Sugar: 6 g

Fats: 25 g

Portion Size: 1/6 of recipe

Total carbs: 43 g

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